The Microarray reinvented—
PathogenDx’s D3
Dynamic Dimensional Detection
Array technology
PathogenDx’s D3
Dynamic Dimensional Detection
Array technology
Technology overview
PathogenDx’s D3 Array is a new approach to multiplexed molecular testing.
The Dynamic Dimensional Detection technology is built upon PathogenDx’s proprietary design of a flexible, solution-facing open architecture, rich with multiple highly accessible probe binding sites. The amplicon target can move easily through the structure, locate probes, and bind with greatly reduced steric hindrance. Consequently, the hybridization reaction becomes more rapid, and can occur at room temperature, thus yielding an increase in affinity while retaining the ability to detect single nucleotide sequence changes (SNP’s).
The Dynamic Dimensional Detection technology is built upon PathogenDx’s proprietary design of a flexible, solution-facing open architecture, rich with multiple highly accessible probe binding sites. The amplicon target can move easily through the structure, locate probes, and bind with greatly reduced steric hindrance. Consequently, the hybridization reaction becomes more rapid, and can occur at room temperature, thus yielding an increase in affinity while retaining the ability to detect single nucleotide sequence changes (SNP’s).
Visualizing the future of multiplexed testing
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Traditional Array Structure
In the traditional array, a probe monolayer is printed directly onto a surface, thereby providing limited binding access to the much longer amplicon target. This reduces target binding affinity due to surface crowding.
3D Open Weave Porous Structure
The PathogenDx next-generation array features a 3D cross-linked structure, with probes suspended away from the surface, that increases access and allows for a faster and higher affinity target amplicon binding reaction.
key features
3D Cross-linked Porous, Flexible Probe Structure
Increases Access; Solution-like Target Probe Binding Interaction
Rapid Room Temperature Hybridization
High Affinity
Minimizes Non-specific Surface Crowding
Increases Fidelity to Enable SNP Detection
Filling the technology gap
Awards & accreditation
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Proven Science To Read About
