Traffic Roots Audience Pixel
Slide
D3 ARRAY™-UTI: FOR THE IDENTIFICATION AND ANALYSIS OF URINARY TRACT PATHOGENS
Today, a wide range of urinary tract conditions are considered either complex or recurrent, creating the need for more complete and rapid insight.
Introducing PathogenDx D3 Array™-UTI, a fast multiplexed testing solution for urinary pathogen detection run simultaneously with antibiotic resistance gene markers. This novel highly multiplexed UTI assay provides a scalable, low cost solution in a single test with results in under 6.5 hours.
GAIN EASE
Test for 26 causative pathogens + 12 Antibiotic Resistance Genes in a single test, with qualitative detection and quantification in the same sample reaction.
STEAMLINE ANALYSIS
Reduce the time and cost of analyzing reams of raw data via PDx’s Augury automated, cloud-based data analysis and management.
RESEARCH EFFICIENTLY
Utilize only the wells you need for each experiment without incurring the added costs of unused wells on the plate —optimizing reagents and consumables spend.
TEST CONFIDENTLY
Deliver higher confidence of results through triplicate testing of each pathogen target and ABR in a single well reaction.
The Need For A New Approach
Urinary tract infections are a common ailment that affects millions of individuals every year. While most UTIs are not serious—and can be identified through the culture-based methods researchers have traditionally relied upon—a surprisingly large population of UTIs present a more complicated scenario.
This has led researchers to consider qPCR methods of molecular testing to gain the results they seek. PathogenDx D3 Array™-UTI introduces a novel, multiplexed alternative that provides, we believe, significant advantages over both classical methods and qPCR for those seeking greater understanding of a growing medical challenge.
Slide

Identifies both the pathogen causing an infection and the antibiotic resistance gene marker in a single reaction well with “built in” redundancy

Slide 2

Delivers Higher Accuracy with Triplicate Testing per target.
■    Quantitation is based on three measurements across three hypervariable regions
■    Built in positive and negative controls—no extra wells required

Slide 3

Equipment Agnostic for Greater Flexibility. D3 Array™-UTI uses standard lab equipment to ease into your testing workflow with savings for knowledge-based organizations.

Slide 4

Gain results faster to keep your workflow humming.

Slide 5

Greater throughput vs other UTI panels—48 samples per plate.

SPEED AND EFFICIENCY OVER PLATING AND qPCR
D3 Array™-UTI concentrates all pathogen and antibiotic resistance targets in a single well, allowing us to optimize UTI testing efficiencies through lower cost reagents and consumables—all without compromising content and quality of the test.
TRUE AUTOMATED,
CLOUD-BASED DATA ANALYSIS

Unlike current qPCR UTI testing solutions that churn out reams of raw data that requires manual analysis simply to complete the process, D3 Array™-UTI is paired with Augury cloud-based automated analysis that identifies target confirmation, avoiding hours of analog heavy-lifting for bioinformaticians, while also providing researchers with the raw data for additional analysis.

NO MORE WASTED WELLS
Too often other testing platforms force labs to waste cost on unused wells because their workflow demands using every well of a plate in a single experiment regardless of the number of samples. With D3 Array™-UTI, we provide built-in flexibility to run the number of wells for only the samples required without losing economics on the rest of the wells of the plate.
Slide
WHAT D3 ARRAY™-UTI TESTS FOR

bacterial species

Acinetobacter baumannii
Aerococcus urinae
Citrobacter (freundii, koseri)
Enterobacter (aerogenes, cloacae)
Enterococcus (faecalis, faecium)
Escherichia coli
Klebsiella (oxytoca, pneumoniae)
Morganella morganii

Mycoplasma (hominis, genitalium)
Proteus (mirabilis, vulgaris)
Providencia stuartii
Pseudomonas aeruginosa
Serratia marcescens
Staphylococcus (aureus, saprophyti-cus)
Streptococcus agalactiae
Ureaplasma (parvum, urea)

Qualitative and Quantitative Detection in the same reaction

Slide 2
WHAT D3 ARRAY™-UTI TESTS FOR

antibiotic resistance gene markers

Tetracycline (tetM)
ESBL (blaTEM, blaSHV, blaCTX-M-1)
Trimethoprim (dfrA1)
Methicilin (mecA)
Quinolone (Gyrase A)
Aminoglycoside (aac6-1b-cr)
Ampicillin (blaACT)

Vancomycin (VanA)
Carbapenem (OXA-48)
Colistin (mcr-1)

fungal species

Candida (albicans, glabrata)

Qualitative and Quantitative Detection in the same reaction

previous arrow
next arrow
THE TOP LINE? NEW EFFICIENCES IN UTI TESTING
  • More flexible, faster and lower cost testing than qPCR or NGS technology
  • Equipment agnostic, compatible with routine molecular instrumentation
  • Simultaneous testing for all targets of interest for greater efficiencies
  • Each sample analyzed in triplicate for Quality Assurance
  • No wasted test wells, use only what you need per run
  • 3D cross-linked array architecture enabling rapid probe binding
  • Reporting, easy and simple—cloud-based, tool-enabled
  • Based on our patented D3 (Dynamic Dimensional Detection) technology
FOR RESEARCH USE ONLY.
NOT FOR USE IN DIAGNOSTIC PROCEDURES.
Learn more about D3 Array™-UTI and PathogenDx.